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forkhead box protein m1 foxm1  (Santa Cruz Biotechnology)


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    Structured Review

    Santa Cruz Biotechnology forkhead box protein m1 foxm1
    The muscarinic agonist increases the phosphorylation of Akt and expression of cyclin D2 protein in mouse islets. ( A ) Phosphorylation of Akt and ( B ) expression of cyclin D2 protein were evaluated in isolated islets from wild-type (WT) mice and insulin-receptor substrate 2 ( IRS-2 ) −/− mice orally administered bethanechol (Bch; 1 µg/g body weight) once a day for 1 week (n = 4–9). ( C ) Protein levels of FoxO1, <t>FoxM1</t> and PDX1 were analysed in WT mice administered Bch (1 µg/g) once a day for 1 week (n = 3–7). The data represent the mean ± standard error of the mean (SEM). * P < 0.05 vs. control.
    Forkhead Box Protein M1 Foxm1, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 97/100, based on 583 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/forkhead box protein m1 foxm1/product/Santa Cruz Biotechnology
    Average 97 stars, based on 583 article reviews
    forkhead box protein m1 foxm1 - by Bioz Stars, 2026-02
    97/100 stars

    Images

    1) Product Images from "The beneficial effects of a muscarinic agonist on pancreatic β-cells"

    Article Title: The beneficial effects of a muscarinic agonist on pancreatic β-cells

    Journal: Scientific Reports

    doi: 10.1038/s41598-019-52691-8

    The muscarinic agonist increases the phosphorylation of Akt and expression of cyclin D2 protein in mouse islets. ( A ) Phosphorylation of Akt and ( B ) expression of cyclin D2 protein were evaluated in isolated islets from wild-type (WT) mice and insulin-receptor substrate 2 ( IRS-2 ) −/− mice orally administered bethanechol (Bch; 1 µg/g body weight) once a day for 1 week (n = 4–9). ( C ) Protein levels of FoxO1, FoxM1 and PDX1 were analysed in WT mice administered Bch (1 µg/g) once a day for 1 week (n = 3–7). The data represent the mean ± standard error of the mean (SEM). * P < 0.05 vs. control.
    Figure Legend Snippet: The muscarinic agonist increases the phosphorylation of Akt and expression of cyclin D2 protein in mouse islets. ( A ) Phosphorylation of Akt and ( B ) expression of cyclin D2 protein were evaluated in isolated islets from wild-type (WT) mice and insulin-receptor substrate 2 ( IRS-2 ) −/− mice orally administered bethanechol (Bch; 1 µg/g body weight) once a day for 1 week (n = 4–9). ( C ) Protein levels of FoxO1, FoxM1 and PDX1 were analysed in WT mice administered Bch (1 µg/g) once a day for 1 week (n = 3–7). The data represent the mean ± standard error of the mean (SEM). * P < 0.05 vs. control.

    Techniques Used: Phospho-proteomics, Expressing, Isolation, Control



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    The muscarinic agonist increases the phosphorylation of Akt and expression of cyclin D2 protein in mouse islets. ( A ) Phosphorylation of Akt and ( B ) expression of cyclin D2 protein were evaluated in isolated islets from wild-type (WT) mice and insulin-receptor substrate 2 ( IRS-2 ) −/− mice orally administered bethanechol (Bch; 1 µg/g body weight) once a day for 1 week (n = 4–9). ( C ) Protein levels of FoxO1, <t>FoxM1</t> and PDX1 were analysed in WT mice administered Bch (1 µg/g) once a day for 1 week (n = 3–7). The data represent the mean ± standard error of the mean (SEM). * P < 0.05 vs. control.
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    The muscarinic agonist increases the phosphorylation of Akt and expression of cyclin D2 protein in mouse islets. ( A ) Phosphorylation of Akt and ( B ) expression of cyclin D2 protein were evaluated in isolated islets from wild-type (WT) mice and insulin-receptor substrate 2 ( IRS-2 ) −/− mice orally administered bethanechol (Bch; 1 µg/g body weight) once a day for 1 week (n = 4–9). ( C ) Protein levels of FoxO1, FoxM1 and PDX1 were analysed in WT mice administered Bch (1 µg/g) once a day for 1 week (n = 3–7). The data represent the mean ± standard error of the mean (SEM). * P < 0.05 vs. control.

    Journal: Scientific Reports

    Article Title: The beneficial effects of a muscarinic agonist on pancreatic β-cells

    doi: 10.1038/s41598-019-52691-8

    Figure Lengend Snippet: The muscarinic agonist increases the phosphorylation of Akt and expression of cyclin D2 protein in mouse islets. ( A ) Phosphorylation of Akt and ( B ) expression of cyclin D2 protein were evaluated in isolated islets from wild-type (WT) mice and insulin-receptor substrate 2 ( IRS-2 ) −/− mice orally administered bethanechol (Bch; 1 µg/g body weight) once a day for 1 week (n = 4–9). ( C ) Protein levels of FoxO1, FoxM1 and PDX1 were analysed in WT mice administered Bch (1 µg/g) once a day for 1 week (n = 3–7). The data represent the mean ± standard error of the mean (SEM). * P < 0.05 vs. control.

    Article Snippet: The lysed islets were subjected to centrifugation and the extracts were subjected to immunoblotting with antibodies to the following proteins: Akt, phospho-Akt, forkhead transcription factor (FoxO1) (Cell Signalling Technology); cyclin D2, forkhead box protein M1 (FoxM1) (Santa Cruz); pancreatic and duodenal homeobox 1 (PDX1) (Merck); or β actin (Abcam).

    Techniques: Phospho-proteomics, Expressing, Isolation, Control